Alias: Valdenafil.HCl , VARDENAFIL, HYDROCHLORIDE SALT
CAS No.: 224785-91-5
Assay: 99%
Appearance: White powder
EINECS:
Molecular formula: C23H34Cl2N6O4S
Molecular weight: 306.44
Molecular structure:
Melting point: 214-216°C
Manufacturer: Xinrunde
Usage: It is pharmaceutical raw material,indicated for the treatment of erectile dysfunction
Product Details
Description
Vardenafil (INN) is a PDE5 inhibitor used for treating erectile dysfunction. Vardenafil's indications and contra-indications are the same as with other PDE5 inhibitors; it is closely related in function to sildenafil citrate () and tadalafil (Cialis). The difference between the vardenafil molecule and sildenafil citrate is a nitrogen atom's position and the change of sildenafil's piperazine ring methyl group to an ethyl group. Tadalafil is structurally different from both sildenafil and vardenafil. Vardenafil's relatively short effective time is comparable to but somewhat longer than sildenafil's. Vardenafil hydrochloride is a prescription medicine with another name vardenafil HCl. It helps those men who have impotence(erectile dysfunction). This medicine will not help you to cure your erectile dysfunction. This drug is needed to be taken only when you want to have a sexual intercourse. "Vardenafil hydrochloride" is a brand name that doesn't mean anything. It was just made up. A new group of drugs was discovered to treat erectile dysfunction. One of the first PDE5 inhibitors that were released for this treatment was . The second similar drug that is available in United States is Vardenafil hydrochloride.Cialis is the third and soon will be on the market. In Europe you may find all three of these drugs. A lot pf people thought that impotence happens because of some psychological reasons. After Vardenafil hydrochloride was discovered, many understood that impotence is only a physical matter. The following factors like high pressure of blood, problems with heart, diabetes and even oldness can be the reasons that will prevent maintaining and obtaining erection. Before such impotence medicine like Levitra, people made implants in their penis or injected something into it. These intrusive and painful treatments are not needed when there is such medicine like Levitra. Most men started to have a successful sexual life taking only one pill. Everyone should know that erectile dysfunction can not be cured with Vardenafil hydrochloride. This drug is used before you are intended to have sexual intercourse. Theerection will be achieved approximately during one hour. After you had sex, the medicine's action just wears off some hours later. There were cases when men had a remaining erection after taking this pill, but usually you need to take another dose once again to have positive effect having sexual intercourse. Don't confuse Levitra with aphrodisiac. This medicine will only help you to have an erection when you have sexual stimulation, it will not make you desire your partner. The medicine influences your body and not your thoughts and your mind. Some people are often asking questions why Levitra doesn't make them horny. They see the difference after several sexual stimulations.Application
Vardenafil hcl is used in the management of erectile dysfunction in men above the age of 18. Erectile dysfunction is a condition wherein the person cannot get proper erections and maintain it for long duration to facilitate sexual intercourse. Although Vardenafil hcl is indicated for erectile dysfunction, it is not effective without proper sexual stimulation. The drug is known to work even in persons who are suffering from other conditions such as hypertension, diabetes or high cholesterol. Beyond its indications for erectile dysfunction, vardenafil may be effective in the treatment of premature ejaculation, where it may significantly increase the time from vaginal penetration to ejaculation. Vardenafil, as with all PDE5 inhibitors, should not be used by men taking nitrate medications, because combining them with vardenafil might provoke potentially life-threatening hypotension (low blood pressure). Beyond its indications for erectile dysfunction, vardenafil may be effective in the treatment of premature ejaculation, where it may significantly increase the time from vaginal penetration to ejaculation. Vardenafil, as with all PDE5 inhibitors, should not be used by men taking nitrate medications, because combining them with vardenafil might provoke potentially life-threatening hypotension (low blood pressure). Further, Vardenafil causing lengthening of the QT interval. Therefore it should not be taken by men taking other medications that affect the QT interval (such as amiodarone).COA
| CERTIFICATE OF ANALYSIS | ||
| Test Items | Specification | Test Results |
| Description | White or almost white crystalline powder | White crystalline powder |
| Melting Point | 191.0~193.0ºC | 192° |
| Loss of drying | ≤1.0% | 0.50% |
| Heavy Metal | ≤20ppm | 15ppm |
| TLC | Only one spot | Only one spot |
| Assay | ≥99.5% | 99.91% |
| Conclusion | It complies with the USP 32. | |
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Dosage
Patients taking Levitra are usually started on a 10 mg dose, which they take no more than once daily, about one hour before sexual activity. It can take as little as 30 minutes for Levitra to work in some patients. Like with , Levitra dosages are adjusted depending on a person's reaction, with doctors generally decreasing doses to to 2.5 mg or increasing them to no more than 20 mg once a day.Vardenafil, as with all PDE5 inhibitors, should not be used by men taking nitrate medications, because combining them with Vardenafil might provoke potentially life-threatening hypotension (low blood pressure).