Description
Lab Test Result:
| Test Items | Specification | Results |
| Description | White crystalline powder | Complies |
| Total Impurity | max.0.5% | 0.18% |
| Total Unspecified Impurity | max. 0.2% | 0.08% |
| Individual unspecified impurlty | max. 0.1% | 0.05% |
| Related compound B | max. 0.2% | 0.07% |
| Related compound C | max. 0.2% | 0.04% |
| Related compound D | max. 0.1% | 0.05% |
| Related compound E | max. 0.1% | 0.06% |
| Limit of cyclohexane | max. 0.08% | 0.05% |
| Limit of ethylacetate | max. 0.1% | 0.07% |
| Melting point | 81.0~84.0ºC | 82.5~83.2ºC |
| Water | max. 0.3% | 0.21% |
| Residue on ignition | max. 0.1% | 0.07% |
| Heavy Metals | max.0.001% | Complies |
| Assay (HPLC) | 98%~102% | 99.2% |
| Conclusion | It complies to USP32 Standard | |
Application
An aromatase inhibitor. Used as an antineoplastic raw materials.Potent selective triazole aromatase inhibitors, can inhibit the cytochrome P-450 aromatase enzyme which depends blocking the biosynthesis of estrogen, and estrogen to stimulate breast cancer cell growth factors. Treatment of breast cancer, especially for those with hormone relapse after adjuvant therapy after menopause for women with advanced breast cancer. The drug is appropriately used when using substantial amounts of aromatizing steroids, or when one is prone to gynecomastia and using moderate amounts of such steroids. Arimidex does not have the side effects of aminoglutethimide (Cytadren) and can achieve a high degree of estrogen blockade, much moreso than Cytadren. It is possible to reduce estrogen too much with Arimidex, and for this reason blood tests, or less preferably salivary tests, should be taken after the first week of use to determine if the dosing is correct.Dosage
Dosages of arimidex will vary from person to person. This is why blood work is essential to finding the perfect balance. One should start out at half a mg every other day and adjust as needed for the cycle. Some AAS users will not use an AI at first but they will have it on hand just in case. This isn't always a good idea, as once you start noticing gyno or excessive water weight it could be too late to reverse. Since AAS will continue building in the body and aromatize, taking arimidex at this point would be like trying to stop a car already in motion. General Dosage For Men: 0.5 mg per day or every other dayAnastrozole VS Letrozole
Aromatase inhibition is the gold standard for treatment of early and advanced breast cancer in postmenopausal women suffering from an estrogen receptor-positive disease. The currently established group of anti-aromatase compounds comprises two reversible aromatase inhibitors (anastrozole and letrozole) and on the other hand, the irreversible aromatase inactivator exemestane. Although exemestane is the only widely used aromatase inactivator at this stage,physicians very often have to choose between either anastrozole or letrozole in general practice.These third-generation aromatase inhibitors Letrozole and Anastrozole, have recently demonstrated superior efficacy compared with tamoxifen as initial therapy for early breast cancer improving disease-free survival. However, although anastrozole and letrozole belong to the same pharmacological class of agents (triazoles), an increasing body of evidence suggests that these aromatase inhibitors are not equipotent when given in the clinically established doses. Preclinical and clinical evidence indicates distinct pharmacological profiles. Thus, this review focuses on the differences between the non-steroidal aromatase inhibitors allowing physicians to choose between these compounds based on scientific evidence. Although we are waiting for the important results of a still ongoing head-to-head comparison in patients with early breast cancer at high risk for relapse, clinicians have to make their choices today. On the basis of available evidence summarised here and until FACE-data become available, letrozole seems to be the best choice for the majority of breast cancer patients whenever a non-steroidal aromatase inhibitor has to be chosen in a clinical setting.
OUR ADWANTAGE
1,High quality with competitive price: 1)Standard: USP Standard 2)All Purity≥99% 3)We are manufacturer and can provide high quality products with factory price. 2,Fast and safe delivery 1)Parcel can be sent out in 24 hours after payment. Tracking number available 2)Secure and discreet shipment. Various transportation methods for your choice. 3)Customs pass rate ≥99% 4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe, and we have stock in there for transferring. 3,We have clients throughout the world. 1)Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire. 2)Market feedback and goods feedback will be appreciated, meeting customers's requirement is our responsibility. 3) High quality,competitive price,fast delivery ,first-class service gain the trust and praise from the customers.Our Related Products
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Hjtc (Xiamen) Industry Co., Ltd.
Xiamen Huayongjian Biotechnology Co., Ltd.
Contacts: June & Eason
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