Tamoxifen Citrate(Nolvadex) Quick details
Tamoxifen Citrate(Nolvadex) Description
Tamoxifen Citrate is the citrate salt of an antineoplastic nonsteroidal selective estrogen receptor modulator (SERM). Tamoxifen competitively inhibits the binding of estradiol to estrogen receptors, thereby preventing the receptor from binding to the estrogen-response element on DNA. The result is a reduction in DNA synthesis and cellular response to estrogen. In addition, tamoxifen up-regulates the production of transforming growth factor B (TGFb), a factor that inhibits tumor cell growth, and down-regulates insulin-like growth factor 1 (IGF-1), a factor that stimulates breast cancer cell growth. Tamoxifen also down-regulates protein kinase C (PKC) expression in a dose-dependant manner, inhibiting signal transduction and producing an antiproliferative effect in tumors such as malignant glioma and other cancers that overexpress PKC. Tamoxifen is currently used for the treatment of both early and advanced estrogen receptor-positive (ER-positive or ER+) breast cancer in pre- and post-menopausal women. Additionally, it is the most common hormone treatment for male breast cancer. It is also approved by the FDA for the prevention of breast cancer in women at high risk of developing the disease.It has been further approved for the reduction of contralateral (in the opposite breast) cancer. The use of tamoxifen is recommended for 10 years. In 2006, the large STAR clinical study concluded that raloxifene is equally effective in reducing the incidence of breast cancer, but after an average 4-year follow-up, although the difference was not statistically significant, there were 36% fewer uterine cancers and 29% fewer blood clots in women taking raloxifene than in women taking tamoxifen.Tamoxifen Citrate(Nolvadex) Application
1. Nolvadex is not an anabolic steroid but is used to manage side effects from steroids. 2. Nolvadex is a mixed estrogen agonist/antagonist of the same type as Clomid. 3. Tamoxifen Citrate is the raw material of Nolvadex. 4. Nolvadex is also a kind of medicine to treat cancer. 5. Nolvadex (tamoxifen citrate) is very comparable to Clomid. 6. Nolvadex behaves in the same manner in all tissues with Clomid. For the treatment of advanced, recurrent breast cancer and ovarian cancer and other illnesses. Used as an antineoplastic raw materials. Biological Activity: Estrogen receptor antagonist/partial agonist. Selective and potent inhibitor of mammalian sterol isomerase. Neuroprotective in female rats in vivo . Also high affinity agonist at the membrane estrogen receptor GPR30. Nolvadex and Clomid are two of the most popular Selective Estrogen Receptor Modulators (SERMs) in the world and part of the supplemental plan for many performance enhancing athletes. More athletes buy Nolvadex for PCT purposes than any other purpose; in-fact, more performance enhancers buy Nolvadex for their PCT use than any other medication available. In-fact, more performance enhancers buy Nolvadex for their PCT use than any other medication available. As you understand the purpose of the PCT period is to stimulate natural testosterone production after a cycle of anabolic steroids has been discontinued; this is necessary as anabolic steroids suppress natural testosterone production. Further, beyond testosterone stimulation this is the period when we begin normalizing our body but in the case of Tamoxifen Citrate it is testosterone production we are concerned with here. Gynecomastia(male breast enlargement) is one of the most worrisome side-effects that can occur due to anabolic androgenic steroid use, fortunately you can buy Nolvadex and combat this effect; no, Tamoxifen Citrate will not reduce the amount of estrogen in your body but it will prevent a large portion of it from binding and this provides protection. Nolvadex is the trade name for the drug tamoxifen citrate, it is a non-steroidal agent that demonstrates potent anti-estrogenic properties. The drug is technically an estrogen agonist/antagonist, which competitively binds to estrogen receptors in various target tissues. With the tamoxifen molecule bound to this receptor, estrogen is blocked from exerting any action, and an anti-estrogenic effect is achieved. Since many forms of breast cancer are responsive to estrogen, the ability of tamoxifen citrate to block its action in such cells has proven to be a very effective treatment. It is also utilized successfully as a preventative measure, taken by people with an extremely high familial tendency for breast cancer. While Nolvadex is effective against estrogen, it is not our strongest available remedy.Since Nolvadex is milder in comparison, it is more widely applicable and usually the first treatment option.Tamoxifen Citrate(Nolvadex) COA
Product name | Tamoxifen citrate (Nolvadex) | |
Appearance | White crystalline powder | |
Identification | IR , UV conform | Conform |
Loss on drying | ≤0.5ml | 0.21ml |
Residue on ignition | Not more than 0.2% | 0.07ml |
Iron | Not more than 0.005% | 0.0017% |
Heavy metals | Not more than 0.001% | 0.0006% |
Related substances | Total: Not more than 1.0% Individual: Not more than 0.5% | 0.35% 0.13% |
E-isomer | Not more than 0.3% | 0.18% |
Organic volatile impurities | Conforms | Conforms |
Assay | 99.0~101.0% | 99.6% |
Packaging & Delivery
1. By Express------Suitable for under 50kg, Fast:3-7 days. High cost; Door to door service. Easy to pick up the goods.
2. By Air ------Suitable for more than 50 kg, Fast:3-7 days, High cost, airport to airport. professional broker needed. 3. By sea ------Suitable for more than 500kg. Slow: 5-45 days, Low cost. Port to Port, professional broker needed.
Frequently Asked Question
Q1:Can I get some raw steroids samples? A:Sure,we can supply the free steroids powder sample,just pay shipping cost. Q2:How to make orders? A:Please send inquiry to us,after we come to an agreement,send payment via Bitcoin, paypal, bank transfer, Wise Transfer, etcthen we ship products out and give tracking number to you. Q3:How to delivery? A:Pack shipped in 2 days(Chinese holiday not included) after payment,usually ship via Fedex,EMS,HKEMS,DHL,TNT,UPS,NL Post,USPS Domestic fast shipping,signature not requested. Q4:Is there any discount? A:Yes.The price is negotiable,If you order large quantity or some products together,you will get discount and enjoy free shipping. Q5:What is the Minimum order quantity? A:The Min. order quantity according to your request,10g,50g all is OK. The price is negotiable,it according to the order quantity,the larger the order is,the better the price is.Our Hot Sale products
Testosterone Steroid |
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No. | CAS NO | Name |
1 | CAS:58-22-0 | Testosterone base |
3 | CAS:76-43-7 | Fluoxymesterone Halotestin |
4 | CAS:2446-23-3 | 4-Chlorodehydromethyltestosterone(Oral turinabol) |
5 | CAS:1255-49-8 | Testosterone Phenylpropionate |
6 | CAS:57-85-2 | Testosterone Propionate |
7 | CAS:1045-69-8 | Testosterone acetate |
8 | CAS:315-37-7 | Testosterone enanthate |
9 | CAS:58-20-8 | Testosterone Cypionate |
10 | CAS:1424-00-6 | Mesterolone (Proviron) |
11 | CAS:5949-44-0 | Testosterone Undecanoate |
12 | CAS:15262-86-9 | Testosterone isocaproate |
13 | CAS:855-19-6 | Turinabol(4-Chlorotestosterone/Clostebol Acetate) |
14 | CAS: NO | Testosterone Sustanon 250/100 |
15 | CAS:5721-91-5 | Testosterone decanoate |
16 | CAS:58-18-4 | Methyltestosterone (17-methyltestosterone) |
17 | CAS:58-20-8 | 1-Test Cyp,Dihydroboldenone Cypionate |
Boldenone Steroid |
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17 | CAS:846-48-0 | Boldenone |
18 | CAS:13103-34-9 | Boldenone Undecylenate (Equipoise) |
19 | CAS:846-46-0 | Boldenone Acetate |
20 | CAS:13103-34-9 | Boldenone Propionate |
21 | CAS:106505-90-2 | Boldenone Cypionate |
Trenbolone Steroid |
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22 | CAS:10161-33-8 | Trenbolone base |
23 | CAS:10161-34-9 | Trenbolone acetate(Finaplix H/Revalor-H) |
24 | CAS:472-61-546 | Trenbolone enanthate(parabolan) |
25 | CAS:23454-33-3 | Trenbolone Hexahydrobenzyl Carbonate |
Nandrolone Steroid |
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26 | CAS:434-22-0 | Nandrolone |
27 | CAS:62-90-8 | Nandrolone Phenypropionate (NPP)/durabolin |
28 | CAS: 601-63-8 | Nandrolone cypionate |
29 | CAS:360-70-3 | Nandrolone decanoate(DECA)/ Deca durabolin |
30 | CAS: 862-89-5 | Nandrolone Undecylate |
31 | CAS: 7207-92-3 | Nandrolone propionate |
Primobolan Steroid |
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32 | CAS:434-05-9 | Methenolone Acetate(Primobolan) |
33 | CAS:303-42-4 | Methenolone enanthate (USAN) |
34 | CAS: 153-00-4 | Metenolone |
35 | CAS:3381-88-2 | Superdrol Powder/Methasterone (methyl-drostanolone) |
36 | CAS:521-12-0 | Drostanolone Propionate (Masteron) |
37 | CAS:472-61-145 | Drostanolone Enanthate(Masteron) |
Anabolic Steroids |
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38 | CAS:72-63-9 | Methandrostenolone (Dianabol, methandienone) |
39 | CAS:3704-09-4 | Mibolerone |
40 | CAS:965-93-5 | Methyltrienolone (Metribolone) |
Contact Us
Hjtc (Xiamen) Industry Co., Ltd.
Xiamen Huayongjian Biotechnology Co., Ltd.
Contacts: June & Eason Whatsapp:+8618206063252; +8618759200098 E-mail: eastern002@126.com;
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Order Guide
how to make order | ||
step1 | Pre-sale service | 1.As for your every inquiries, we always reply timely and patiently. All of the relevant information will be provided to help you to make a wise choice |
2. if you need we can offer provide you with COA , Cook Recipes Of Steroid Oil , Feedback Of Other Customers | ||
Step2 | payment | 1.we'd like to accept Bitcoin, paypal, bank transfer, Wise Transfer, etc |
Step3 | delivery | 2.we are support Transportation: DHL, UPS, TNT, EMS, Hongkong EMS, FedEx or Other |
3.After confirming your payment, shipping arrangement and package pictures will be provided within 24 Hours ; Tracking number will be provided within 72 Hours. | ||
4.For important parcel information, such as: Left Original Country , Arrived At Destination Country , Passed Customs , Out For Delivery , Delivered, those information will be sent to you timely. | ||
Step4 | After-sales service | 1.you could consult us for any questions, we offer 7*24h good servies and Tech-support. |
After Sales Service
1.Quality steroid powder and Favorable pricesFavorable prices 2.Newest and updated discreet ways 3.The most professional express 4.One to one Exclusive customer service 5.Flexible and Untraceable payment terms 6.24/7 online helpful After-sale serviceOur advantages
1. Guarantee 100% genuine powder high purity quality
2. 10g min. order
3. Can ship 25kg at a time
4. Discount on multiple items or large order
5. Shipping with Special disguised packaging, 99.9% success rate.Resend policy
6. Injectable steroid. We offer melting powder into liquid service.
Tamoxifen Citrate(Nolvadex) Functions & Traits
Tamoxifen Citrate is a SERM with both estrogen agonist and antagonist properties. As an anti-estrogen, Nolvadex functions by binding to the estrogen receptors in the place of estrogen. This binding prevents the estrogen hormone from performing its action in certain parts of the body, which is precisely why it's beneficial to breast cancer patients. Many forms of breast cancer actually feed off estrogen when it attaches to the receptors in the chest. By preventing the attachment in such receptors, this also protects anabolic steroid users from gynecomastia, which can be caused by anabolic steroids that aromatize such as , Dianabol, andNandrolone to a degree. While primarily viewed as an anti-estrogen, Nolvadex also has the ability to act as estrogen, specifically in the liver. This presents a benefit as estrogenic activity in the liver has been linked to healthier cholesterol levels. For the steroid user, this can be extremely beneficial as many anabolicsteroids tend to have an adverse effect on cholesterol. More on this when we look at the direct effects of Nolvadex later on. Although primarily an anti-estrogen, Nolvadex also possess strong testosterone stimulating characteristics. Nolvadex has the ability to block the negative feedback that is brought on by estrogen at the hypothalamus and pituitary. As a result, this stimulates an enhanced release by the pituitary of Luteinizing Hormone (LH) and Follicle Stimulating Hormone (FSH). Both LH and FSH are essential to natural testosterone production. Without LH and FSH, with an even stronger emphasis on LH, there is no natural testosterone production.