SR9011 Abstract
SR9011 is a potent and specific synthetic REV-ERB agonist that binds to REV-ERB-α with an EC50 ~790nM and REV-ERB-β with EC50 ~560 nM. It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB-α and REV-ERB-β play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism. Administration of SR9011 alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice. The circadian expression pattern of an array of metabolic genes in the liver, skeletal muscle and adipose tissue was also altered, resulting in increased energy expenditure. Treatment of diet-induced obese mice with SR9011 decreased obesity by reducing fat mass and markedly improved dyslipidaemia and hyperglycaemia. These results indicate that synthetic REV-ERB ligands that pharmacologically target the circadian rhythm may be beneficial in the treatment of sleep disorders as well as metabolic diseases.SR9011 Not Just a "Diet" Pill
There's no way to sugarcoat it-though many have tried-maintaining a healthy weight can be difficult. Because it's hard, many have tried "miracle" weight-loss pills and other quick fixes for something that ultimately requires a lifestyle change. Many over-the-counter diet and weigh-loss pills are unregulated and may contain dangerous ingredients. SR9011, however, isn't like appetite suppressants, laxatives, or "fat blockers." And you won't find SR9011 in the ingredient lists of protein powders or exercise supplements. The difference between SR9009 and other diet pills is in its chemistry. SR9011 is not an appetite suppressant-as many weight-loss drugs are-and directly works by increasing the metabolic rate of muscle. Your metabolism speeds up and slows down naturally during the day, meaning that sometimes food is used for energy and sometimes it's stored as fat. By re-synching a dysfunctional metabolic clock, SR9011 ensures that food and excess fat are used as energy. SR9011 is one of a pair of compounds developed at TSRI by Burris and his team. The drug binds to Rev-erbα,a natural protein in the body that influences lipid and glucose metabolism in the liver, inflammatory responses, and fat-storing cells. By binding to Rev-erbα, SR9011 can kickstart metabolism with another pleasant side-effect: increased muscle strength.SR9009 VS SR9011
The difference between SR9009 and other diet pills is in its chemistry. SR9011 is not an appetite suppressant-as many weight-loss drugs are-and directly works by increasing the metabolic rate of muscle. Your metabolism speeds up and slows down naturally during the day, meaning that sometimes food is used for energy and sometimes it's stored as fat. By re-synching a dysfunctional metabolic clock, SR9011 ensures that food and excess fat are used as energy.Our advantage
1. Rich experience. Our company is a professional manufacturer leading in China in pharmaceutical area .We specialize in this field for 19 years. Our steroids and pharmaceutical raw materials have been exported to the whole world.We have got very good feedback from our customers, and established long friendly relations of cooperation. 2. Great quality, purity and favorable. Our products are after repeated extraction, multiple detection,good quality is one secret for our success. Welcome order the samples, MOQ just 10 grams. 3. Safest and fastest delivery. Safe and professional disguised package can be guaranteed.We have adequate stock, we can arrange the delivery within 24hours when receiving the payment. Tracking number would be informed quickly after shipment. We have special way which could ship 0.01 kilo to 50 kilo products a time.Provide door-to-door delivery. 4. Good after-sales service. 24/7 is available. Tell the package update info ASAP. And try our best to solve various problems customers encounter timely! 5. Experiential shopping Besides raw steroid powder and liquid, we offer hormone solution and formula. We can teach you how to make hormone solution on the site. We also provide semi-finished products, only need to filter by yourself, can be used as a finished product.
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Q1:How to confirm the Product Quality before placing orders? A:free samples is available,but freight charges will be at your account and the charges will be return to you or deduct from your order in the future. Q2:Can you give me a discount price? A:Surely,It depend on your qty.Larger order can enjoy cheaper price. Q3:When you ship my order? A:Normally within 2 to 3 days after confirming your payment,because we need time to arrange Stealth Packing for 100% customs clearance. Q4:Can you guarantee I can get my goods without any custom problem? Yes, We have Reship Service.You can get your goods without any problem. Q5:How do you treat quality complaint? A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us,we will send you free goods for replacement or refund your loss. Q6:Which kind of payment terms do you accept? A:For any order,you can pay by Paypal,Bitcoin,T/T,Western Union or Money Gram. Q7: How to contact with us? A:We use email, whatsapp, wickr me, wechat,ect. so pls be free to contact me if you have any needs.Contact Us
Hjtc (Xiamen) Industry Co., Ltd.
Xiamen Huayongjian Biotechnology Co., Ltd.
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