BPC157 abstract
BPC157 Description
BPC 157 is a pentadecapeptide, meaning that is comprised of a chain of 15 amino acids. It has been determined to be a partial sequence of body protection compound (BPC) that can be isolated from gastric juices located in animal test subjects. It possesses a molecular mass of 1419.53552, and its molecular formula is C62H98N16O22. It can be referred to by the alternate names BPC 15, BPC-157, or Booly Protection Compound 15. Pentadecapeptide BPC 157, composed of 15 amino acids, is a partial sequence of body protection compound (BPC) that is discovered in and isolated from human gastric juice. Experimentally it has been demonstrated to accelerate the healing of many different wounds, including transected rat Achilles tendon. This study was designed to investigate the potential mechanism of BPC 157 to enhance healing of injured tendon. The outgrowth of tendon fibroblasts from tendon explants cultured with or without BPC 157 was examined. Results showed that BPC 157 significantly accelerated the outgrowth of tendon explants. Cell proliferation of cultured tendon fibroblasts derived from rat Achilles tendon was not directly affected by BPC 157 as evaluated by MTT assay. However, the survival of BPC 157-treated cells was significantly increased under the H(2)O(2) stress. BPC 157 markedly increased the in vitro migration of tendon fibroblasts in a dose-dependent manner as revealed by transwell filter migration assay. BPC 157 also dose dependently accelerated the spreading of tendon fibroblasts on culture dishes. The F-actin formation as detected by FITC-phalloidin staining was induced in BPC 157-treated fibroblasts. The protein expression and activation of FAK and paxillin were determined by Western blot analysis, and the phosphorylation levels of both FAK and paxillin were dose dependently increased by BPC 157 while the total amounts of protein was unaltered. In conclusion, BPC 157 promotes the ex vivo outgrowth of tendon fibroblasts from tendon explants, cell survival under stress, and the in vitro migration of tendon fibroblasts, which is likely mediated by the activation of the FAK-paxillin pathway. BPC 157 has a strong anti-inflammatory activity in both acute and chronic inflammation models. In fact, preliminary results in clinical trials suggest that BPC 157 may become an important therapeutic tool for the treatment of inflammatory bowel disease. BPC 157 was shown to accelerate wound healing and to have a marked angiogenic effect. In addition, it significantly facilitates the healing of bone fracture in rats. This peptide also exhibits an osteogenic effect significantly improving the healing of segmental bone defect. BPC 157 accelerates the healing of transected rat Achilles tendon and transected rat quadriceps muscle. BPC 157 is a pentadecapeptide, meaning that is comprised of a chain of 15 amino acids. It has been determined to be a partial sequence of body protection compound (BPC) that can be isolated from gastric juices located in animal test subjects. It possesses a molecular mass of 1419.53552, and its molecular formula is C62H98N16O22. It can be referred to by the alternate names BPC 15, BPC-157, or Booly Protection Compound 15. Increased ligament healing Has a variety of protective effects in the organs Human trials demonstrate healing and prevention of stomach ulcers No adverse reactions have been seen in human trials.BPC157 Effect
The main characteristics of healing are granulation tissue, angiogenesis and production of collagen. BPC-157 facilitates angiogenesis. Angio (vessel) genesis (formation) is the formation of vessels. No, seriously its that dumb. Take any 2 words, say them out of order in greek and/or Latin and you get the medical term. BPC-157 acts by modulating Vaso Endothelial Factor (VEGF) which is the factor that causes capillaries to grow into a new area to carry blood and nutrients. This is how healing happens, through blood flow. This only occurred in actual tendon and muscle tissue, in cell cultures BPC-157 did not affect VEGF or healing. BPC 157 Benifits BPC 157 has been shown in rat studies to heal torn quadriceps muscles, detached achilles tendon, muscles that have been damaged/crushed Dramatic fast recovery from muscle tears Tendon to bone healingBPC157 Dose
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Testosterone Series | Methenolone Series | ||
Product Name | CAS.No | Product Name | CAS.No |
Testosterone Enanthate | 315-37-7 | Methenolone Enanthate | 303-42-4 |
Testosterone | 58-22-0 | Methenolone Acetate | 434-05-9 |
Testosterone Acetate | 1045-69-8 | Oral Steroids | |
Testosterone Propionate | 57-85-2 | Product Name | CAS.No |
Testosterone Cypionate | 58-20-8 | Oxymetholone (Anadrol) | 434-07-1 |
Testosterone Phenylpropionate | 1255-49-8 | Oxandrolone (Anavar,Oxandrin) | 53-39-4 |
Testosterone Isocaproate | 15262-86-9 | Stanozolol(winstrol) | 10418-03-8 |
Testosterone Decanoate | 5721-91-5 | Methandienone (Dianabol) | 72-63-9 |
Testosterone Undecanoate | 5949-44-0 | SARMS | |
Sustanon 250 | Product Name | CAS.No | |
Nandrolone Series | Cardarine (GW-501516) | 317318-70-0 | |
Product Name | CAS.No | Andarine (S4) | 401900-40-1 |
Nandrolone | 434-22-0 | Ligandrol (LGD-4033) | 1165910-22-4 |
Nandrolone Decanoate | 360-70-3 | Ibutamoren (MK-677) | 159752-10-0 |
Nandrolone phenylpropionate | 62-90-8 | RAD140 | 118237-47-0 |
Trenbolone Series | SR9009 | 1379686-30-2 | |
Product Name | CAS.No | YK11 | 431579-34-9 |
Trenbolone | 10161-33-8 | Ostarine (MK-2866) | 841205-47-8 |
Trenbolone Acetate | 10161-34-9 | Sex Enhancement | |
Trenbolone Enanthate | 10161-33-8 | Product Name | CAS.No |
Boldenone Series | Tadalafil (Cialis) | 171596-29-5 | |
Product Name | CAS.No | Sildenafil citrate | 171599-83-0 |
Boldenone | 846-48-0 | Vardenafil | 224789-15-5 |
Boldenone undecylenate | 13103-34-9 | hydrochloride | 119356-77-3 |
DEHA | Dutasteride (Avodart) | 164656-23-9 | |
Product Name | CAS.No | Finasteride | 98319-26-7 |
Epiandrosterone | 481-29-8 | Yohimbine HCl (Extract) | 65-19-0 |
Dehydroisoandrosterone (DHEA) | 53-43-0 | Pain Killer | |
Dehydroisoandrosterone 3-acetate | 853-23-6 | Product Name | CAS.No |
7-Keto-dehydroepiandrosterone | 566-19-8 | Phenacetin | 62-44-2 |
Drostanolone Series | Benzocaine | 1994/9/7 | |
Product Name | CAS.No | Lidocaine HCL | 23239-88-5 |
Drostanolone Propionate | 521-12-0 | Paracetamol | 103-90-2 |
Drostanolone Enanthate | 472-61-1 | Dimethocaine | 136-47-0 |
Methasterone | 3381-88-2 | Dyclonine HCL | 854056-07-6 |
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Hjtc (Xiamen) Industry Co., Ltd.
Xiamen Huayongjian Biotechnology Co., Ltd.
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