Description
When you train, what happens to your muscles is they break down, the cells are damaged, muscle tissue needs to be repaired and your body produces 2 forms of MGF splice variant. The first initial release of the above mentioned number 1 variant from the liver helps muscle cell recovery, if there is no MGF then muscle cells die. As muscle is a post-mitotic tissue and as such cell replacement is not a means of tissue repair, if the cells are not repaired they die and your muscles get smaller and weaker. In muscle tissue, the pool of these stem cells is apparently replenished by the action of MGF, which is produced as a pulse following damage. Now, with synthetic injections of MGF you can increase the pulse and so speed up recovery, and increase the muscle tissue cells by stimulating satellite cells into full maturity. In terms of dosages, 200mcg bi-laterally is the very best choice of dosing in muscles trained. The only problem with MGF, and this is the reason I don't like it, is that it has such a short half life, just a few minutes, between 5-7, and it needs to be used immediately post workout as it wont work if muscle tissue hasn't been damaged. That's why, for me personally, I think the best option is PEG MGF. Nevertheless, MGF has a huge role to play, and is administered to those with muscle wasting diseases and for those who are elderly and have lost muscle mass for good reason, it is EXTREMELY anabolic.How To Use MGF
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Application
Mechano growth factor (MGF) is a novel splice variant of the Insulin-Like Growth Factor-1 (IGF-1), also known as IGF-1 Ec in humans and IGF-1Eb in rodents. It is actually originally called MGF because the RNA form of it is expressed in muscle tissues in response to the overload or/and damage of muscle growth tissue. The C-terminal peptide of the mechano growth factor (MGF) is a crucial region for the alternative splicing of the peptide.Dosage
A typical protocol would be:100-300mcg of MGF divided into 1-2 bilateral administrations in 2-5 different areas of the muscles approximately 5-7 days a week - intramuscular injections.
Example, if you want to administer 200mcg of MGF into the chest and biceps muscles 2 times a day and 3 different areas of the muscle then you would need to divided the dose as follows:
200mcg / 2 times per day = 100mcg per administration
100mcg per administration / 4 muscles (2 chest and 2 bicep muscles) = 25mcg per muscle
25mcg per muscle / 3 different locations on each muscle = 8.3mcg per injection
Theoreticall, the more locations used to administer the MGF into the muscle the more places for muscle growth.
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Description
Mechano Growth Factor (MGF) also known as IGF-1Ec is a growth factor/repair factor that is derived from exercised or damaged muscle tissue. It's called MGF as IGF-IEa is a bit of a mouthful and harder to identify amongst the other IGF variants. What makes MGF special is its' unique role in muscle growth. MGF has the ability to cause wasted tissue to grow and improve by activating muscle stem cells and increasing the upregulation of protein synthesis, this unique ability can rapidly improve recovery and speed up muscle growth. MGF can initiate muscle satellite (stem) cell activation in addition to its IGF-1 receptor domain which, in turn, increases protein synthesis turnover; therefore, if used correctly it can improve muscle mass over time.