Hexarelin Description
Hexarelin is a six-amino acid peptide. Studies have shown that hexarelin is actually more effective and longer lasting than growth hormone releasing hormone (GHRH). It is also known that GHRP-6 has a synergistic effect with GHRH, causing a far greater release than either of these substances alone. By combining GHRP-6 with Hexarelin, a more potent GH releasing peptide combination is created than ever heard of. The potential clinical usefulness of these GH releasing hexapeptides is also reinforced by observations that long-term administration produces elevations in circulating IGF-1 concentrations. Long term treatment with GHRP-6 similarly has been shown to elevate serum IGF-1 as well as IGF-binding protein-3 concentrations and promote linear growth. Hexarelin comes in a freeze dried powder just like the other GHRP peptides and storage should be done in a cool dry place until reconstituted and placed in a refrigerator. Bacteriostatic water is used to reconstitute the powder and an insulin syringe is the preferred method for administering subcutaneous injections of hexarelin. Users will notice 200mcgs is the saturation dose for hexarelin and over a few weeks of use total desensitization may begin to take place. Also, the occasional flare up of the pituitary has been noted when dosing far beyond saturation doses. Desensitization can be cleared easily by taking a break from hexerlin usage for a few days to a few weeks. This GHRP is the strongest, and because of the desensitization factor, I believe the optimal way to use this peptide would be to blend it at low doses with other GHRP's like GHRP2,GHRP6 or iPamorelin.Hexarelin Application
Hexarelin is an appetite-regulating factor secreted from peripheral organs that is involved in regulation of energy homoeostasis via binding to the receptor resulting in the secretion of by the pituitary gland.The pathway activated by binding of Hexarelin to the secretagogue receptor,GHSR1a, regulates the activation of the downstream mitogen-activated protein kinase, Akt, nitricoxide synthase, and AMPK cascades in different cellular systems.One of the important features of GHSR1a displays constitutive activity possessing basal activity in the absence of an agonist, resulting in a high degree of receptor internalization as well as of signaling activity.Inverse agonists for the Hexarelin receptor could be particularly interesting for the treatment of obesity.This activity seems to provide a tonic signal required for the development of normal height, probably through an effect on the GH axisHexarelin Benefits
Interestingly, the most amazing finding with hexarelin was its ability to act on cardiac receptors separate from the GH releasing properties. The peptide can directly aid in cardio protective left ventricular pressure issues, as well as, help healing scar tissue on the heart. Studies on lean and obese lab rats concluded that while lean rats were able to take advantage of the GH plasma increase better than the obese rats (the healthier the rat the more hexarelin effectively produced and utilized GH), obese rats did not see the same advantage. Separate from the studies that monitored GH, both lean and obese rats both received all of the cardio protective properties of hexarelin.The functionality of Hexarelin
Hexarelin Secretion
Peptide Products
| Peptide | |
| MGF (2mg) | HGH 176-191 (2mg) |
| PEG MGF (2mg) | CJC-1295 (2mg) |
| DSIP (2mg) | CJC-1295 DAC (2mg) |
| TB500 (2mg) | GHRP-2 (5mg / 10mg) |
| Oxytocin (2mg) | GHRP-6 (5mg / 10mg) |
| Hexarelin (2mg) | Selank (5mg) |
| Triptorelin (2mg) | Epitalon (10mg) |
| Ipamorelin (2mg) | PT-141 (10mg) |
| Sermorelin (2mg) | Melanotan I (10mg) |
| Gonadorelin (2mg / 10mg) | Melanotan II (10mg) |
| Tesamorelin (2mg) | ACE031 (1mg) |
| BPC157 (2mg) | Follistatin 315 (1mg) |
| AOD9604 (2mg) | Follistatin 344 (1mg) |
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